API Co., Ltd.--Making People Healthy with Honeybees

These proteins are produced by API’s proprietary platform technologies with use of S2 cells, a drosophila embryo-derived cell line.
They're characterized with a high level of activity due to posttranslational modifications such as glycosylation. Such posttranslational modifications make the expressed protein maintain a three-dimensional structure which resembles the natural state.

Recombinant human activin A (for laboratory use)

Activin A is a homodimer of two βA chains, each containing 116 amino acid residues. It is a cytokine which belongs to TGF-β family with a molecular weight of about 26,000 and responsible for functions such as inducing stem cell (iPS/ES cells) differentiation into mesoderm and endoderm.

Product features

• • Manufacturing with use of insect cells (non-BEVS): Genes are delivered chemically without using a virus vector.
• • Stable quality: We are capable of consistent manufacturing of high-quality activin with a stable expressing cell line.

Product content

• • Lyophilized. 10 μg, 50 μg, or 0.5 mg per vial of recombinant human activin A
  (Composition: 150 μg/ml activin A and citric acid/phosphoric acid buffer, sterilized with a 0.2 μm filter)
• • Host: Drosophila melanogaster-derived S2 cells
  *This product is for laboratory use only. It cannot be used for purposes other than laboratory use.

Product specifications

• • Activin A content: ≥ 10 μg/tube (code no.: GF-001-010L)　
  　　　　　　　　　　≥ 50 μg/tube (code nos.: GF-001-050L and GF-001-500L)
• • Activin A concentration: 150 μg/mL
• • Verification test: Bands found at 20 to 25 kDa (non-reduced), bands found at 10 to 15 kDa (reduced)
• • Purity: ≥ 90%
• • Endotoxin test: < 50 EU/mg
• • Potency: ≥ 0.5 × 103 IU/mg